Protein complex identification by supervised graph local clustering

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Protein complex identification by supervised graph local clustering

MOTIVATION Protein complexes integrate multiple gene products to coordinate many biological functions. Given a graph representing pairwise protein interaction data one can search for subgraphs representing protein complexes. Previous methods for performing such search relied on the assumption that complexes form a clique in that graph. While this assumption is true for some complexes, it does n...

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ژورنال

عنوان ژورنال: Bioinformatics

سال: 2008

ISSN: 1367-4803,1460-2059

DOI: 10.1093/bioinformatics/btn164